Centro de Química

Publicações

Artigo

Development of Thermo- and pH-Sensitive Liposomal Magnetic Carriers for New Potential Antitumor Thienopyridine Derivatives

Beatriz C. Ribeiro; Cristina A. R. Alvarez; Bárbara C. Alves; Juliana M. Rodrigues; Maria João R. P. Queiroz; Bernardo G. Almeida; Ana Pires; André M. Pereira; João P. Araújo; Paulo J. G. Coutinho; Ana Rita O. Rodrigues; Elisabete M. S. Castanheira

Materials , 2022

Artigo

Magnetoliposomes Containing Multicore Nanoparticles and a New Antitumor Thienopyridine Compound with Potential Application in Chemo/Thermotherapy

Fábio A. C. Lopes; André V. F. Fernandes; Juliana M. Rodrigues; Maria-João R. P. Queiroz; Bernardo G. Almeida; Ana Pires; André M. Pereira; João P. Araújo; Elisabete M. S. Castanheira; Ana Rita O. Rodrigues; Paulo J. G. Coutinho

Biomedicines , 2022

Artigo

Magnetoliposomes Based on Magnetic/Plasmonic Nanoparticles Loaded with Tricyclic Lactones for Combined Cancer Therapy

Irina S. R. Rio; Ana Rita O. Rodrigues; Juliana M. Rodrigues; Maria-João R. P. Queiroz; R. C. Calhelha; Isabel C. F. R. Ferreira; Bernardo G. Almeida; Ana Pires; André M. Pereira; João P. Araújo; Elisabete M. S. Castanheira; Paulo J. G. Coutinho

Pharmaceutics , 2021

Artigo

Rhodium(III)‐Catalyzed Formal Cycloaddition between Thienopyridine/Thienopyrazine Carboxylic Acids and Alkynes, Triggered by C−H Activation

Juliana M. Rodrigues; Borja Cendón; Moisés Gulías; José Luis Mascareñas; Maria‐João R. P. Queiroz

European Journal of Organic Chemistry , 2021

Artigo

Synthesis of Novel Methyl 3-(hetero)arylthieno[3,2-b]pyridine-2-carboxylates and Antitumor Activity Evaluation: Studies In Vitro and In Ovo Grafts of Chick Chorioallantoic Membrane (CAM) with a Triple Negative Breast Cancer Cell Line

Bruna R. Silva; Rita Rebelo; Juliana M. Rodrigues; Cristina P. R. Xavier; M. Helena Vasconcelos; Maria-João R. P. Queiroz

Molecules , 2021

Artigo

Synthesis of Novel Methyl 7-[(Hetero)arylamino]thieno[2,3-b]pyrazine-6-carboxylates and Antitumor Activity Evaluation: Effects in Human Tumor Cells Growth, Cell Cycle Analysis, Apoptosis and Toxicity in Non-Tumor Cells

Juliana M. Rodrigues; Ricardo C. Calhelha; António Nogueira; Isabel C. F. R. Ferreira; Lillian Barros; Maria-João R. P. Queiroz

Molecules , 2021

Artigo

Application of PEG400 in the one-pot synthesis of 7-[4-alkyl- or (hetero)aryl-1H-1,2,3-triazol-1-yl]thieno[3,2-b]pyridines via SNAr and Cu(I)-Catalyzed Azide-Alkyne Cycloaddition and preliminary evaluation of their anti-tumour activity

Rodrigues, J.M.; Calhelha, R.C.; Ferreira, I.C.F.R.; Queiroz, M.-J.R.P.

Tetrahedron Letters , 2020

Artigo

Development of multifunctional liposomes containing magnetic/plasmonic MnFe 2 O 4 /Au core/shell nanoparticles

Rodrigues, A.R.O.; Matos, J.O.G.; Nova Dias, A.M.; Almeida, B.G.; Pires, A.; Pereira, A.M.; Araújo, J.P.; Queiroz, M.-J.R.P.; Castanheira, E.M.S.; Coutinho, P.J.G.

Pharmaceutics , 2019

Artigo

Magnetoliposomes containing calcium ferrite nanoparticles for applications in breast cancer therapy

Pereira, D.S.M.; Cardoso, B.D.; Rodrigues, A.R.O.; Amorim, C.O.; Amaral, V.S.; Almeida, B.G.; Queiroz, M.-J.R.P.; Martinho, O.; Baltazar, F.; Calhelha, R.C.; Ferreira, I.C.F.R.; Coutinho, P.J.G.; Castanheira, E.M.S.

Pharmaceutics , 2019

Artigo

Novel dehydropeptide-based magnetogels containing manganese ferrite nanoparticles as antitumor drug nanocarriers

Sérgio R. S. Veloso; Carlos A. B. Magalhães; Ana Rita O. Rodrigues; H. Vilaça; Maria-João R. P. Queiroz; J. A. Martins; Paulo J. G. Coutinho; Paula M. T. Ferreira; Elisabete M. S. Castanheira

Physical Chemistry Chemical Physics , 2019

Artigo

Synthesis of novel 8-(het)aryl-6H-pyrano[4′,3′:4,5]thieno[3,2-b]pyridines by 6-endo-dig cyclization of Sonogashira products and halolactonizations with Cu salts/NXS. Preliminary antitumor evaluation

Rodrigues, J.M.; Buisson, P.; Pereira, J.M.; Pinheiro, I.M.; Fernández-Marcelo, T.; Vasconcelos, M.H.; Berteina-Raboin, S.; Queiroz, M.-J.R.P.

Tetrahedron , 2019

Livro

Magnetoliposomes for dual cancer therapy

Rodrigues, Ana Rita O.; Almeida, Bernardo G.; Araújo, João P.; Queiroz, Maria-João R.P.; Coutinho, Paulo J.G.; Castanheira, Elisabete M.S.

Inorganic Frameworks as Smart Nanomedicines , 2018

Artigo

Synthesis of New Annulated Pyrazinothienotriazolopyrimidinones and Triazolylthienopyrazines

Campos, J.F.; Queiroz, M.-J.R.P.; Berteina-Raboin, S.

Synthesis (Germany) , 2018

Artigo

The first catalytic direct C-H arylation on C2 and C3 of thiophene ring applied to thieno-pyridines, -pyrimidines and -pyrazines

Campos, J.F.; Queiroz, M.-J.R.P.; Berteina-Raboin, S.

Catalysts , 2018

Artigo

Magnetoliposomes as carriers for promising antitumor thieno[3,2-b]pyridin-7-arylamines: photophysical and biological studies

Rodrigues, A.R.O.; Almeida, B.G.; Rodrigues, J.M.; Queiroz, M.J.R.P.; Calhelha, R.C.; Ferreira, I.C.F.R.; Pires, A.; Pereira, A.M.; Araújo, J.P.; Coutinho, P.J.G.; Castanheira, E.M.S.

RSC Advances , 2017

Artigo

Solid and aqueous magnetoliposomes as nanocarriers for a new potential drug active against breast cancer

Rodrigues, A.R.O.; Mendes, P.M.F.; Silva, P.M.L.; Machado, V.A.; Almeida, B.G.; Araújo, J.P.; Queiroz, M.-J.R.P.; Castanheira, E.M.S.; Coutinho, P.J.G.

Colloids and Surfaces B: Biointerfaces , 2017

Artigo

Synthesis of New Thieno[3, 2-b]pyridines and Thieno[2, 3-b]pyrazines by Palladium Cross-Coupling

Campos, J.F.; Queiroz, M.J.R.P.; Berteina-Raboin, S.

ChemistrySelect , 2017

Artigo

Antiangiogenic 1-Aryl-3-[3-(thieno[3,2-b]pyridin-7-ylthio)phenyl]ureas Inhibit MCF-7 and MDA-MB-231 Human Breast Cancer Cell Lines Through PI3K/Akt and MAPK/Erk Pathways

Machado, V.A.; Peixoto, D.; Queiroz, M.J.; Soares, R.

Journal of Cellular Biochemistry , 2016

Artigo

Chemical characterization, antioxidant, anti-inflammatory and cytotoxic properties of bee venom collected in Northeast Portugal

Sobral, F.; Sampaio, A.; Falcão, S.; Queiroz, M.J.R.P.; Calhelha, R.C.; Vilas-Boas, M.; Ferreira, I.C.F.R.

Food and Chemical Toxicology , 2016

Artigo

Effect of substitution on the ultrafast deactivation of the excited state of benzo[: B] thiophene-arylamines

Pina, J.; Queiroz, M.-J.R.P.; Seixas De Melo, J.

Photochemical and Photobiological Sciences , 2016

Ver mais

Equipa

Maria João Queiroz

ORCID

CIÊNCIA VITAE

SCOPUS ID

Publicações

154

H-index

39

Estudantes PhD

10

Projetos

3

Publicações

Development of Thermo- and pH-Sensitive Liposomal Magnetic Carriers for New Potential Antitumor Thienopyridine Derivatives

Magnetoliposomes Containing Multicore Nanoparticles and a New Antitumor Thienopyridine Compound with Potential Application in Chemo/Thermotherapy

Magnetoliposomes Based on Magnetic/Plasmonic Nanoparticles Loaded with Tricyclic Lactones for Combined Cancer Therapy

Rhodium(III)‐Catalyzed Formal Cycloaddition between Thienopyridine/Thienopyrazine Carboxylic Acids and Alkynes, Triggered by C−H Activation

Synthesis of Novel Methyl 3-(hetero)arylthieno[3,2-b]pyridine-2-carboxylates and Antitumor Activity Evaluation: Studies In Vitro and In Ovo Grafts of Chick Chorioallantoic Membrane (CAM) with a Triple Negative Breast Cancer Cell Line

Synthesis of Novel Methyl 7-[(Hetero)arylamino]thieno[2,3-b]pyrazine-6-carboxylates and Antitumor Activity Evaluation: Effects in Human Tumor Cells Growth, Cell Cycle Analysis, Apoptosis and Toxicity in Non-Tumor Cells

Application of PEG400 in the one-pot synthesis of 7-[4-alkyl- or (hetero)aryl-1H-1,2,3-triazol-1-yl]thieno[3,2-b]pyridines via SNAr and Cu(I)-Catalyzed Azide-Alkyne Cycloaddition and preliminary evaluation of their anti-tumour activity

Development of multifunctional liposomes containing magnetic/plasmonic MnFe 2 O 4 /Au core/shell nanoparticles

Magnetoliposomes containing calcium ferrite nanoparticles for applications in breast cancer therapy

Novel dehydropeptide-based magnetogels containing manganese ferrite nanoparticles as antitumor drug nanocarriers

Synthesis of novel 8-(het)aryl-6H-pyrano[4′,3′:4,5]thieno[3,2-b]pyridines by 6-endo-dig cyclization of Sonogashira products and halolactonizations with Cu salts/NXS. Preliminary antitumor evaluation

Magnetoliposomes for dual cancer therapy

Synthesis of New Annulated Pyrazinothienotriazolopyrimidinones and Triazolylthienopyrazines

The first catalytic direct C-H arylation on C2 and C3 of thiophene ring applied to thieno-pyridines, -pyrimidines and -pyrazines

Magnetoliposomes as carriers for promising antitumor thieno[3,2-b]pyridin-7-arylamines: photophysical and biological studies

Solid and aqueous magnetoliposomes as nanocarriers for a new potential drug active against breast cancer

Synthesis of New Thieno[3, 2-b]pyridines and Thieno[2, 3-b]pyrazines by Palladium Cross-Coupling

Antiangiogenic 1-Aryl-3-[3-(thieno[3,2-b]pyridin-7-ylthio)phenyl]ureas Inhibit MCF-7 and MDA-MB-231 Human Breast Cancer Cell Lines Through PI3K/Akt and MAPK/Erk Pathways

Chemical characterization, antioxidant, anti-inflammatory and cytotoxic properties of bee venom collected in Northeast Portugal

Effect of substitution on the ultrafast deactivation of the excited state of benzo[: B] thiophene-arylamines

Projetos

Self-assembled minimalist peptide hydrogels inspired by mussel adhesive proteins for biomedical applications

Sistemas nanoestruturados para desempenho sob medida

Novos biomarcadores de imagem na avaliação das oclusões coronárias crónicas totais

Estudantes PhD

Ricardo Calhelha

Rafaela Guimarães

Juliana Rodrigues

Sandrina Heleno

Solange Carvalho

Vera Machado

Ana Abreu

Isabel Ferreira

Maria Martins

Rui Abreu